This Policy Note highlights the vital role of women-owned sari-sari stores in shaping the Philippine socioeconomic landscape. Using the Participation-Empowerment framework and the Human Flourishing Index, this study assesses how these microenterprises contribute significantly to women’s empowerment and human flourishing while fostering social capital and community engagement. Based on survey data from 311 female store owners in Central Luzon and Metro Manila, the research examines their empowerment across various dimensions. Findings indicate that women entrepreneurs experience a sense of pride, purpose, and confidence, viewing their businesses as tools for financial independence and family support. However, challenges persist, including limited access to capital, inadequate business skills, and restricted government engagement. Statistical analysis confirms a strong correlation between entrepreneurship and well-being, linking sari-sari store ownership with social connectedness and resilience. The study recommends addressing information gaps, refining intervention programs, and recognizing sari-sari stores as integral to the care economy.